The girl, who died following the the incident involving a tram and a van, was named as Louisa ‘Lulu’ Palmisano, from Burnley.
In a statement, Greater Manchester Police said Rawal Rehman, 35, from Manchester, was charged with causing death by dangerous driving.
Police previously said emergency services responded to reports of a road traffic collision in Manchester city centre at around 10am on Saturday.
They said a van collided with a tram, which forced the van on to a pavement where it collided with a pedestrian.
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